JAM-A Protein, Mouse, Recombinant (His)

Ref. TM-TMPK-00188

Informação sobre produto

• Nome: JAM-A Protein, Mouse, Recombinant (His)
• Sinónimos: F11R, JCAM1, PAM-1, PAM-1KAT, JAM-1, JAM, JCAM, JAM-A, KAT, F11 receptor, CD321

Descrição

junctional adhesion molecule A (JAM-A), a cell adhesion molecule, is highly elevated in human GBM cancer stem cells and predicts poor patient prognosis. While JAM-A is also highly expressed in other cells in the tumor microenvironment, specifically microglia and macrophages,JAM-A functions to suppress pathogenic microglial activation in the female tumor microenvironment, highlighting an emerging role for sex differences in the GBM microenvironment and suggesting that sex differences extend beyond previously reported tumor cell-intrinsic differences.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 23.9 kDa (predicted). Due to glycosylation, the protein migrates to 28-35 kDa based on Tris-Bis PAGE result.
• Cor/forma: Solid