SIRP alpha V3 Protein, Human, Recombinant (His & Avi)

Ref. TM-TMPK-00625

Informação sobre produto

• Nome: SIRP alpha V3 Protein, Human, Recombinant (His & Avi)
• Sinónimos: P84, SIRP alpha, CD172a, MFR, MYD-1, PTPNS1, SIRPA, SHPS1, MYD1, SIRP α, BIT, SHPS-1, SIRP α V3

Descrição

Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don't eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.8 kDa and the accession number is ATD50864.1.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 39.8 kDa (predicted). Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
• Cor/forma: Solid