LILRB4/CD85k/ILT3 Protein, Cynomolgus, Recombinant (His)

Ref. TM-TMPK-01312

Informação sobre produto

• Nome: LILRB4/CD85k/ILT3 Protein, Cynomolgus, Recombinant (His)
• Sinónimos: LIR5, CD85K, HM18, LILRB4, ILT3, ILT-3

Descrição

LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k/ILT3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 27.2 kDa and the accession number is XP_015297198.1.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 27.2 kDa (predicted). Due to glycosylation, the protein migrates to 35-42 kDa based on Tris-Bis PAGE result.
• Cor/forma: Solid