Voacangine

CAS: 510-22-5

Ref. TM-TN5246

Informação sobre produto

• Nome: Voacangine
• Sinónimos: (-)-Voacangine, 10-Methoxycoronaridine, 6,9-Methano-5H-pyrido[1′,2′:1,2]azepino[4,5-b]indole, ibogamine-18-carboxylic acid deriv., Carbomethoxyibogaine, Ibogamine-18-Carboxylic Acid, 12-Methoxy-, Methyl Ester, (2Alpha)-, Ibogamine-18-carboxylic acid, 12-methoxy-, methyl ester
• CAS: 510-22-5

Descrição

Voacangine is a selective and potent antagonist of TRPV1 and TRPM8, and an agonist of TRPA1, with an EC50 value of 8 μM for TRPA1. Voacangine inhibits the binding of menthol to TRPM8 with an IC50 value of 9 μM, and icilin with an IC50 value of 7 μM. Voacangine selectively eliminates chemical agonist-induced activation of TRPM8, but not cold-induced activation. Voacangine is extracted from the root bark of the American Sorbus Voacanga africana.

• Marca: Targetmol

Propriedades químicas

• Peso molecular: 368.47
• Fórmula: C₂₂H₂₈N₂O₃
• Pureza: 98%
• Cor/forma: Solid