3b-Acetoxyandrost-5-en-17-one Acetylhydrazone

CAS: 75980-86-8

Ref. TR-A164315

Informação sobre produto

• Nome: 3b-Acetoxyandrost-5-en-17-one Acetylhydrazone
• Sinónimos: Acetic Acid [(3ß)?-?3-?(Acetyloxy)?androst-?5-?en-?17-?ylidene]?hydrazide

Descrição

Applications 3β-Acetoxyandrost-5-en-17-one Acetylhydrazone is an impurity of Pregnenolone (P712200) which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A.
References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976), Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001), Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002), Abe, C., et al.: Lipids, 42, 637 (2007)

• Marca: TRC

Propriedades químicas

• Peso molecular: 386.53
• Fórmula: C₂₃H₃₄N₂O₃
• Cor/forma: Neat
• InChI: InChI=1S/C23H34N2O3/c1-14(26)24-25-21-8-7-19-18-6-5-16-13-17(28-15(2)27)9-11-22(16,3)20(18)10-12-23(19,21)4/h5,17-20H,6-13H2,1-4H3,(H,24,26)/b25-21+/t17-,18-,19-,20-,22-,23-/m0/s1
• Chave InChI: InChIKey=HOUBKUBIMXTSHD-PACONACKSA-N
• SMILES: CC(=O)N/N=C1\CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(C)=O)CC[C@]4(C)[C@H]3CC[C@]12C