2-(Acetylamino)-2-deoxy-D-glucose 1-Oxime 3,4,6-Triacetate

CAS: 908353-02-6

Ref. TR-A164325

Informação sobre produto

• Nome: 2-(Acetylamino)-2-deoxy-D-glucose 1-Oxime 3,4,6-Triacetate
• Sinónimos: [(2R,3R,4R,5S,6E)-5-acetamido-3,4-diacetyloxy-2-hydroxy-6-hydroxyiminohexyl] acetate
• Marca: TRC
• Descrição: Applications 2-(Acetylamino)-2-deoxy-D-glucose 1-Oxime 3,4,6-Triacetate is an intermediate in the synthesis of O-(2-Acetamido-2-deoxy-D-glucopyranosylidene)amino N-Phenylcarbamate (A157250), which is an inhibitor of O-GlcNAcase, hexosaminidase A, and hexosaminidase B.References Baji, H., et al,: Eur. J. Med. Chem., 30, 617 (1995), Vaaje-Kolstad, G., et al.: J. Biol. Chem., 279, 3612 (2004), Perreira, M., et al.: Bioorg. Med. Chem., 14, 837 (2006).

Propriedades químicas

• Peso molecular: 362.33
• Fórmula: C₁₄H₂₂N₂O₉
• Cor/forma: Neat
• InChI: InChI=1S/C14H22N2O9/c1-7(17)16-11(5-15-22)13(24-9(3)19)14(25-10(4)20)12(21)6-23-8(2)18/h5,11-14,21-22H,6H2,1-4H3,(H,16,17)/b15-5+/t11-,12+,13+,14+/m0/s1
• Chave InChI: InChIKey=XXURLVBLRDQUJU-UBHIWVTISA-N
• SMILES: CC(=O)N[C@@H](/C=N/O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H](O)COC(C)=O