N-Acetyl Lorcaserin-d3

CAS: 1181690-72-1

Ref. TR-A185202

Informação sobre produto

• Nome: N-Acetyl Lorcaserin-d3
• Sinónimos: 1-[(5R)-7-chloro-5-methyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl]-2,2,2-trideuterioethanone

Descrição

Applications N-Acetyl Lorcaserin-d3 is the isotope labelled analog of N-Acetyl Lorcaserin (A185200); an impurity of Lorcaserin (L469890, HCl) which is a novel selective 5-HT2C-receptor agonist for the treatment of obesity. N-Acetyl Lorcaserin is also used as a reagent in the synthesis of isoquinoline, isoindoline, and benzoazepine amides as therapeutic modulators of the histamine H3 receptor.
References Pauli, M., et al.: Formulary, 45, 180 (2010); Ioannides-Demos, L.L., et al.: J. Obesity, 18, 179674 (2011); Santora, V.J., et al.: PCT Int. Appl. WO 2009105206 A1 20090827. Aug 27, 2009

• Marca: TRC

Propriedades químicas

• Peso molecular: 240.744
• Fórmula: C₁₃D₃H₁₃ClNO
• Cor/forma: Neat
• InChI: InChI=1S/C13H16ClNO/c1-9-8-15(10(2)16)6-5-11-3-4-12(14)7-13(9)11/h3-4,7,9H,5-6,8H2,1-2H3/t9-/m0/s1/i2D3
• Chave InChI: InChIKey=MBRQQRJEBYRWMN-IZTXOYSKSA-N
• SMILES: [2H]C([2H])([2H])C(=O)N1CCc2ccc(Cl)cc2[C@@H](C)C1