N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin

CAS: 219137-85-6

Ref. TR-A189765

Informação sobre produto

• Nome: N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin
• Sinónimos: Caspase-1 Substrate VI, Fluorogenic, N-Acetyl-Tyr-Val-Ala-Asp 7-Amido-4-Trifluoromethylcoumarin, Caspase-1 Substrate Xii, Fluorogenic, Caspase 1 (Ice) Substrate 2F, Fluorogenic, Ac-Yvad-Afc, Ac-Tyr-Val-Ala-Asp-7-Amino-4-Trifluoromethyl Coumarin, Ac-Tyr-Val-Ala-Asp-Afc, N-Acetyl-Tyr-Val-Ala-Asp-(7-amino-4-trifluoromethylcoumarin)
• CAS: 219137-85-6

Descrição

Applications N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin is a substrate whose amino acids are shown as a preferred cleavage site for Caspase-1 and 4. Useful for caspase research.
References Talanian, R. et al.: J. Biol. Chem., 272, 9677 (1977); Marcelli, M. et al.: Cancer Res., 58, 76 (1998);

• Marca: TRC

Propriedades químicas

• Peso molecular: 719.67
• Fórmula: C₃₃H₃₆F₃N₅O₁₀
• Cor/forma: Neat
• InChI: InChI=1S/C33H36F3N5O10/c1-15(2)27(40-30(47)23(39-17(4)42)11-18-5-8-20(43)9-6-18)31(48)38-16(3)29(46)41-28(32(49)50)24(44)14-37-19-7-10-21-22(33(34,35)36)13-26(45)51-25(21)12-19/h5-10,12-13,15-16,23,27-28,37,43H,11,14H2,1-4H3,(H,38,48)(H,39,42)(H,40,47)(H,41,46)(H,49,50)/t16-,23-,27-,28-/m0/s1