Adapalene Dimer Impurity

Ref. TR-A225005

Informação sobre produto

• Nome: Adapalene Dimer Impurity
• Sinónimos: Di-6-(4-methoxyphenyl)-2-naphthoic Acid Adamantane
• Marca: TRC
• Descrição: Applications Adapalene Dimer Impurity is an impurity in the synthesis of Adapalene (A225000), a retinoid selective for retinoic acid receptor (RAR) subtypes β and γ. Antiacne.References Griffiths, C.E.M., et al.: J. Invest. Dermatol., 101, 325 (1993); Bernard, B.A., et al.: Skin Pharmacol., 6, 61 (1993); Waugh, J., et al.: Drugs, 64, 1465 (2004)

Propriedades químicas

• Peso molecular: 688.81
• Fórmula: C₄₆H₄₀O₆
• Cor/forma: Neat
• InChI: InChI=1S/C46H40O6/c1-51-41-13-11-34(30-3-5-32-20-36(44(47)48)9-7-28(32)18-30)22-39(41)43-38-16-26-15-27(17-38)25-46(43,24-26)40-23-35(12-14-42(40)52-2)31-4-6-33-21-37(45(49)50)10-8-29(33)19-31/h3-14,18-23,26-27,38,43H,15-17,24-25H2,1-2H3,(H,47,48)(H,49,50)/t26-,27+,38?,43-,46?/m0/s1
• Chave InChI: InChIKey=KTKWBKKFGAIHTE-NEKSIXODSA-N
• SMILES: COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1[C@@H]1[C@H]2C[C@@H]3C[C@H](C2)C[C@@]1(c1cc(-c2ccc4cc(C(=O)O)ccc4c2)ccc1OC)C3