S-(5'-Adenosyl)-L-methionine-13C5 Sulfate Salt (Synthetic)(Mixture of Diastereomers) (>85%)

CAS: 24346-00-7

Ref. TR-A291533

Informação sobre produto

• Nome: S-(5'-Adenosyl)-L-methionine-13C5 Sulfate Salt (Synthetic)(Mixture of Diastereomers) (>85%)
• Sinónimos: 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine-13C5 Disulfate, 5'-[(L-3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine-13C5 Disulfate, S-Adenosylmethionine-13C5 Disulfate, Active Methionine-13C5 Disulfate, Ademetionine-13C5 Disulfate, L-S-Adenosylmethionin-13C5 Disulfate, S-Adenosyl-L-methionine-13C5 Disulfate, (3-amino-3-carboxypropyl){[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}methylsulfonium chloride (non-preferred name), (3S)-5'-((3-Amino-3-carboxypropyl)methylsulphonio)-5'-deoxyadenosine chloride, <span class="text-smallcaps">L</span>-Methionine, adenosine deriv., Adenosine, 5′-[(3-amino-3-carboxypropyl)methylsulfonio]-5′-deoxy-, chloride, Adenosine, 5′-[(3-amino-3-carboxypropyl)methylsulfonio]-5′-deoxy-, chloride, (3S)-, Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, chloride, Adenosine, 5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-, chloride (1:1), Methionine, S-(5-deoxyadenos-5-yl)-, chloride, <span class="text-smallcaps">L</span>-, S-(5-Adenosyl)-<span class="text-smallcaps">L</span>-methionine chloride, S-Adenosyl-<span class="text-smallcaps">L</span>-methionine chloride, S-Adenosylmethionine chloride, [(3S)-3-amino-3-carboxypropyl]{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}methylsulfonium chloride (non-preferred name)

Descrição

Stability Hygroscopic
Applications Labelled S-(5'-Adenosyl)-L-methionine Disulfate Salt (A291530). Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.
References Friedel, H., et al.: Drugs, 38, 389 (1989), Lu, S., et al.: Int. J. Biochem. Cell Biol., 32, 391 (2000), Amin, K., et al.: Pharm. Res., 18, 914 (2001),

• Marca: TRC

Propriedades químicas

• Peso molecular: 404.4197079808
• Fórmula: C₁₀₁₃C₅H₂₃N₆O₅S•HSO₄•xH₂SO₄
• Pureza: >85%
• Cor/forma: Neat