Allotetrahydrocorticosterone

CAS: 600-63-5

Ref. TR-A548495

Informação sobre produto

• Nome: Allotetrahydrocorticosterone
• Sinónimos: (3alpha,5alpha,11beta)-3,11,21-Trihydroxypregnan-20-one, 3alpha,11beta,21-Trihydroxy-5alpha-pregnan-20-one, 3alpha,5alpha-Tetrahydrocorticosterone, 5alpha-Pregnane-3alpha,11beta,21-triol-20-one, 5alpha-THB, 5alpha-Tetrahydrocorticosterone, 3alpha,11beta,21-Trihydroxy-5alpha-pregnan-20-one, (3Alpha,5Alpha,11Beta)-3,11,21-Trihydroxypregnan-20-One, (3α,5α,11β)-3,11,21-Trihydroxypregnan-20-one, (4-Hydroxycyclohexyl)Acetic Acid, 3α,11β,21-Trihydroxy-5α-pregnan-20-one, 3α,5α-Tetrahydrocorticosterone, 5α-Pregnan-20-one, 3α,11β,21-trihydroxy-, 5α-THB, 5α-Tetrahydrocorticosterone, NSC 112288, Pregnan-20-one, 3,11,21-trihydroxy-, (3α,5α,11β)-

Descrição

Applications Allotetrahydrocorticosterone displays the profile of a safe topical anti-inflammatory compound. Also, it strongly inhibits 11β-HSD2 and 11β-HSD1 dehydrogenase activity.
References Gastaldello, A., et al.: Biochem. Pharmacol., 129, 73-84 (2017); Morris, D. J., et al.: Steroids, 79, 44-48 (2014)

• Marca: TRC

Propriedades químicas

• Peso molecular: 350.49
• Fórmula: C₂₁H₃₄O₄
• Cor/forma: Neat
• InChI: InChI=1S/C21H34O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12-17,19,22-24H,3-11H2,1-2H3/t12-,13+,14-,15-,16+,17-,19+,20-,21-/m0/s1
• Chave InChI: InChIKey=RHQQHZQUAMFINJ-NZTKVECHSA-N
• SMILES: C[C@]12C[C@H](O)[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)CO