AM 404-d4

CAS: 1185244-71-6

Ref. TR-A575812

Informação sobre produto

• Nome: AM 404-d4
• Sinónimos: (5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl-d4)-5,8,11,14-eicosatetraenamide, (all-Z)-N-(4-Hydroxyphenyl-d4)-5,8,11,14-eicosatetraenamide

Descrição

Applications It is a labelled metabolite of the well-known analgesic Paracetamol. AM404 inhibits endocannabinoid cellular uptake, binds weakly to CB1 and CB2 cannabinoid receptors, and is formed by fatty acid amide hydrolase (FAAH) in vivo.
References Basile, S., et al.: Pain, 52, 217 (1993), Beltramo, M., et al.: Science, 277, 1094 (1997), Bisogno, T., et al.: J. Biol. Chem., 272, 3315 (1997), Nicholson, R., et al.: Brain Res., 978, 194 (2003), La Rana, G., et al.: J. Pharmacol. Exp. Ther., 317, 1365 (2006),

• Marca: TRC

Propriedades químicas

• Peso molecular: 399.6
• Fórmula: C₂₆H₃₃D₄NO₂
• Cor/forma: Light Beige Solid
• InChI: InChI=1S/C26H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26(29)27-24-20-22-25(28)23-21-24/h6-7,9-10,12-13,15-16,20-23,28H,2-5,8,11,14,17-19H2,1H3,(H,27,29)/b7-6-,10-9-,13-12-,16-15-/i20D,21D,22D,23D
• Chave InChI: InChIKey=IJBZOOZRAXHERC-GPETUTDJSA-N
• SMILES: [2H]c1c([2H])c(NC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)c([2H])c([2H])c1O