2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)-phenyl)-2-methylpropanenitrile

CAS: 915019-52-2

Ref. TR-A593845

Informação sobre produto

• Nome: 2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)-phenyl)-2-methylpropanenitrile
• Sinónimos: 4-[(3-Amino-6-bromo-4-quinolinyl)amino]-α,α-dimethylbenzeneacetonitrile, 2-[4-[(3-Amino-6-bromoquinolin-4-yl)amino]phenyl]-2-methylpropionitrile
• Marca: TRC

Descrição

Applications 2-(4-((3-Amino-6-bromoquinolin-4-yl)amino)-phenyl)-2-methylpropanenitrile is used as a reagent in the preparation of imidazo quinoline derivatives, compounds that act as mammalian target of rapamycin (mTOR) an phosphatidylinositol 3-kinase (PI3K-kinase) inhibitors.
References Li, X., et al. Imidazo Quinoline Derivative as mTOR and PI3K-kinase Inhibitor Useful In the Treatment of Various Diseases, and Its Preparation. PCT Int. Appl. 2013053273. Apr 18, 2013.

Propriedades químicas

• Peso molecular: 381.27
• Fórmula: C₁₉H₁₇BrN₄
• Cor/forma: Neat
• InChI: InChI=1S/C19H17BrN4/c1-19(2,11-21)12-3-6-14(7-4-12)24-18-15-9-13(20)5-8-17(15)23-10-16(18)22/h3-10H,22H2,1-2H3,(H,23,24)
• SMILES: CC(C)(C#N)c1ccc(Nc2c(N)cnc3ccc(Br)cc23)cc1