(S)-(+)-2-Amino-4-bromobutyric Acid Hydrobromide (~90%)

CAS: 15159-65-6

Ref. TR-A602465

Informação sobre produto

• Nome: (S)-(+)-2-Amino-4-bromobutyric Acid Hydrobromide (~90%)
• Sinónimos: (2S)-2-Amino-4-bromobutyric Acid Hydrobromide, (S)-2-Amino-4-bromobutyric Acid Hydrobromide, L-2-Amino-4-bromobutyric Acid Hydrobromide, (S)-(+)-2-Amino-4-bromobutyric acid hydrobromide, (2S)-2-amino-4-bromobutanoic acid, (2S)-2-amino-4-bromobutanoic acid hydrobromide, L(+)-2-Amino-4-Bromobutyric Acid Hydrobromide

Descrição

Stability Unstable in Solution, Moisture Sensitive, Hygroscopic
Applications (S)-(+)-2-Amino-4-bromobutyric Acid Hydrobromide is a building block used in stereoselective preparation of phosphinic acid phosphapeptide analogs of glutamyl-γ-glutamate as potent inhibitors of folylpolyglutamate synthetase. Also used in the synthesis of isoindoline carbamate and acylsulfonamide containing macrocyclic peptidomimetics as inhibitors of HCV NS3/4A protease.
References Bartley, D., et al.: J. Org. Chem., 70, 6757 (2005); Jiang, Y., et al.: J. Med. Chem., 57, 1753 (2014);

• Marca: TRC

Propriedades químicas

• Peso molecular: 182.028091
• Fórmula: C₄H₈BrNO₂•(HBr)
• Pureza: ~90%
• Cor/forma: Neat
• InChI: InChI=1S/C4H8BrNO2.BrH/c5-2-1-3(6)4(7)8;/h3H,1-2,6H2,(H,7,8);1H/t3-;/m0./s1
• Chave InChI: InChIKey=JDLMXICGDYZOJH-DFWYDOINSA-N
• SMILES: Br.N[C@@H](CCBr)C(=O)O