4-Amino-1-tert-butyl-3-(1’-naphthylmethyl)pyrazolo[3,4-d]pyrimidine

CAS: 221244-14-0

Ref. TR-A603003

Informação sobre produto

• Nome: 4-Amino-1-tert-butyl-3-(1’-naphthylmethyl)pyrazolo[3,4-d]pyrimidine
• Sinónimos: 1-NM-PP1
• Marca: TRC

Descrição

Applications A highly potent (IC50=4.3 nM) and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase.
References Bishop, A.C., et al.: J. Am. Chem. Soc., 121, 627 (1999), Davies, S., et al.: Biochem. J., 351, 95 (2000), Regan, J., et al.: J. Med. Chem., 45, 2994 (2002), Bain, J., et al.: Biochem. J., 371, 199 (2003), Kuma, Y., et al.: J. Biol. Chem., 280, 19472 (2005),

Propriedades químicas

• Peso molecular: 331.41
• Fórmula: C₂₀H₂₁N₅
• Cor/forma: Neat
• InChI: InChI=1S/C20H21N5/c1-20(2,3)25-19-17(18(21)22-12-23-19)16(24-25)11-14-9-6-8-13-7-4-5-10-15(13)14/h4-10,12H,11H2,1-3H3,(H2,21,22,23)
• Chave InChI: InChIKey=GDQXJQSQYMMKRA-UHFFFAOYSA-N
• SMILES: CC(C)(C)n1nc(Cc2cccc3ccccc23)c2c(N)ncnc21