(2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide Hydrochloride

CAS: 1243259-19-9

Ref. TR-A612500

Informação sobre produto

• Nome: (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide Hydrochloride
• Sinónimos: [S-(R*,R*)]-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide Dihydrochloride, LM11A 31 Dihydrochloride

Descrição

Stability Hygroscopic
Applications (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide is used for the preparation of peptideamides for treatment of retroviral infection. This compound has neuroprotective properties.Generally used in Alzheimers Disease, Neuroprotective, Hippocampal neural progenitors. Blood brain barrier (BBB) penetrable, orally bioactive. Blocks p75-medicated cell death.(1) Shows prominent effect against Huntington’s Disease in mice. (2)
References Simmons DA, et al. 2014. PLoS One. Aug 25;9(8):e102136Simmons DA, et al. 2016. Hum Mol Genet. Sep 16

• Marca: TRC

Propriedades químicas

• Peso molecular: 243.35 + 2(36.46)
• Fórmula: C₁₂H₂₅N₃O₂· 2HCl
• Cor/forma: Neat
• InChI: InChI=1S/C12H25N3O2.2ClH/c1-3-10(2)11(13)12(16)14-4-5-15-6-8-17-9-7-15;;/h10-11H,3-9,13H2,1-2H3,(H,14,16);2*1H/t10-,11-;;/m0../s1
• Chave InChI: InChIKey=LLIHJRRZJDEKLB-ULEGLUPFSA-N
• SMILES: CC[C@H](C)[C@H](N)C(=O)NCCN1CCOCC1.Cl.Cl