9-Amino-1,2,3,4-tetrahydroacridine Hydrochloride Dihydrate

CAS: 1684-40-8

Ref. TR-A629700

Informação sobre produto

• Nome: 9-Amino-1,2,3,4-tetrahydroacridine Hydrochloride Dihydrate
• Sinónimos: 9-Acridinamine, 1,2,3,4-tetrahydro-, hydrochloride (1:1), 9-Acridinamine, 1,2,3,4-tetrahydro-, monohydrochloride (9CI), Acridine, 9-amino-1,2,3,4-tetrahydro-, hydrochloride (7CI), Acridine, 9-amino-1,2,3,4-tetrahydro-, monohydrochloride (8CI), 1,2,3,4-Tetrahydro-9-aminoacridine hydrochloride, 5,6,7,8-Tetrahydroacridin-9-amine hydrochloride, 9-Amino-1,2,3,4-Tetrahydroacridine hydrochloride, CI 970, Cognex, Hydroaminacrine, Romotal, THA, Tacrin hydrochloride, Tacrine hydrochloride, Tenakrin, 1,2,3,4-Tetrahydroacridin-9-Amine, 1,2,3,4-Tetrahydroacridin-9-Aminium Chloride, 9-Acridinamine, 1,2,3,4-tetrahydro-, hydrochloride (1:1), 9-Acridinamine, 1,2,3,4-tetrahydro-, monohydrochloride, Acridine, 9-amino-1,2,3,4-tetrahydro-, hydrochloride, Acridine, 9-amino-1,2,3,4-tetrahydro-, monohydrochloride, Ci 970, Furfurylmercaptan

Descrição

Applications A potent centrally acting anticholinesterase, for therapy of memory deficits in patients with Alzheimers's disease. THA also selectively blocks potassium channels in the central nervous system, which results in an increased release of acetylcholine and a prolongation of the action potential of the presynaptic cholinergic neurons.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Harper, J., et al.: Chem. Biol., 4, 119 ( 1997), Kirkitadze, M., et al.: J. Mol. Biol., 312, 1103 (2001), Zhuang, Z., et al.: J. Med. Chem., 44, 1905 (2001), Necula, M.J., et al.: Biol. Chem., 282, 10311 (2007),

• Marca: TRC

Propriedades químicas

• Peso molecular: 234.72
• Fórmula: C₁₃H₁₄N₂·ClH
• Cor/forma: Neat
• InChI: /h1,3,5,7H,2,4,6,8H2,(H2,14,15), InChI=1S/C13H14N2.ClH/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13, 1H
• Chave InChI: InChIKey=ZUFVXZVXEJHHBN-UHFFFAOYSA-N
• SMILES: Cl.Nc1c2c(nc3ccccc13)CCCC2