Anhydro Abiraterone

CAS: 154229-20-6

Ref. TR-A637910

Informação sobre produto

• Nome: Anhydro Abiraterone
• Sinónimos: 3-Androsta-3,5,16-trien-17-yl-pyridine, Anhydroabiraterone

Descrição

Applications Anhydro Abiraterone is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)

• Marca: TRC

Propriedades químicas

• Peso molecular: 331.49
• Fórmula: C₂₄H₂₉N
• Cor/forma: Neat
• InChI: InChI=1S/C24H29N/c1-23-13-4-3-7-18(23)8-9-19-21-11-10-20(17-6-5-15-25-16-17)24(21,2)14-12-22(19)23/h3,5-8,10,15-16,19,21-22H,4,9,11-14H2,1-2H3/t19-,21-,22-,23-,24+/m0/s1
• Chave InChI: InChIKey=GHCZAUBVMUEKKP-RMUYMDBTSA-N
• SMILES: C[C@@H](CCC(=O)NCC(=O)O)[C@@H]1CC[C@@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C