Anhydro Vinblastine-d3 Disulfate Salt

CAS: 1219117-51-7 81165-17-5

Ref. TR-A659752

Informação sobre produto

• Nome: Anhydro Vinblastine-d3 Disulfate Salt
• Sinónimos: 3',4'-Didehydro-4'-deoxyvincaleukoblastine-d3 Disulfate Salt, (+)-Anhydrovinblastine-d3 Disulfate Salt, 3',4'-Anhydrovinblastine-d3 Disulfate Salt, 3',4'-Dehydroisoleurosine-d3 Disulfate Salt, 3',4'-Dehydrovinblastine -d3 Disulfate Salt, 3',4'-Didehydroisoleurosine-d3 Disulfate Salt, Anhydrovincaleukoblastine-d3 Disulfate Salt, F 81097-d3 Disulfate Salt
• CAS: 1219117-51-7 81165-17-5

Descrição

Applications Anhydrovinblastine showed significant cytotoxic potential against a panel of human cancer cell lines and significant activity against the human H460 non-small cell lung carcinoma tumor xenograph in mice.
References Koiso, Y., et al.: J. Antibiot., 51, 418 (1998), Olver, I., et al.: Eur. J. Cancer, 43, 1829 (2007), Shao, Y., et al.: Bioorg. Med. Chem., 15, 5061 (2007).

• Marca: TRC

Propriedades químicas

• Peso molecular: 992.13
• Fórmula: C₄₆H₅₇D₃N₄O₁₆S₂
• Cor/forma: Neat
• InChI: InChI=1S/C46H56N4O8/c1-8-28-21-29-24-45(41(52)56-6,37-31(15-19-49(25-28)26-29)30-13-10-11-14-34(30)47-37)33-22-32-35(23-36(33)55-5)48(4)39-44(32)17-20-50-18-12-16-43(9-2,38(44)50)40(58-27(3)51)46(39,54)42(53)57-7/h10-14,16,21-23,29,38-40,47,54H,8-9,15,17-20,24-26H2,1-7H3/t29-,38-,39?,40-,43-,44-,45-,46+/m1/s1/i6D3
• Chave InChI: InChIKey=FFRFGVHNKJYNOV-OVIKGCCXSA-N
• SMILES: [2H]C([2H])([2H])OC(=O)[C@@]1(c2cc3c(cc2OC)N(C)C2[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]4(CC)C=CCN5CC[C@]32[C@H]54)C[C@H]2C=C(CC)CN(CCc3c1[nH]c1ccccc31)C2