4-Chloroacetoacetyl Chloride

CAS: 41295-64-1

Ref. TR-A733510

Informação sobre produto

• Nome: 4-Chloroacetoacetyl Chloride
• Sinónimos: 4-chloro-3-oxobutanoyl chloride, 4-Chloro-3-Oxobutanoyl Chloride, 4-Chloroacetoacetyl chloride, Butanoyl chloride, 4-chloro-3-oxo-, γ-Chloroacetoacetyl chloride, 4-Chloro-3-oxobutyryl chloride

Descrição

Applications 4-Chloroacetoacetyl Chloride is an impurity of Amlodipine Besylate(A633500); is a dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive. 4-Chloroacetoacetyl Chloride is used in preparation of Dioxohexanoate by Chlorination of Methyleneoxetanone followed by condensation with Meldrum's acid and esterification.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996); Noti, C., et al.: U.S., (2016);

• Marca: TRC

Propriedades químicas

• Peso molecular: 154.979
• Fórmula: C₄H₄Cl₂O₂
• Cor/forma: Neat
• InChI: InChI=1S/C4H4Cl2O2/c5-2-3(7)1-4(6)8/h1-2H2
• Chave InChI: InChIKey=WSHVQVCBPLNREW-UHFFFAOYSA-N
• SMILES: O=C(Cl)CC(=O)CCl