Astemizole-d3

CAS: 1189961-39-4

Ref. TR-A790032

Informação sobre produto

• Nome: Astemizole-d3
• Sinónimos: 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxy-d3-phenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine, Astemisan-d3, Hismanal-d3, Histamen-d3, Paralergin-d3, R 42512-d3, R 43512-d3, Retolen-d3, Waruzol-d3
• CAS: 1189961-39-4

Descrição

Applications Labelled Astemizole. Nonsedating-type histamine H1-receptor antagonist. Potential for combination therapy with antivancer drugs such as doxorubicin in resistant leukemia. Antihistaminic.
References Wauquier, A., et al.: Eur. J. Pharmacol., 72, 245 (1981), Laduron, P.M., et al.: Mol. Pharmacol., 21, 294 (1982), Richards, D.M., et al.: Drugs, 28, 38 (1984), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs., 20, 173 (1991), Ishikawa, M., et al.: Biol. Pharm. Bull., 23, 112 (2000),

• Marca: TRC

Propriedades químicas

• Peso molecular: 461.59
• Fórmula: C₂₈H₂₈D₃FN₄O
• Cor/forma: Neat
• InChI: InChI=1S/C28H31FN4O/c1-34-25-12-8-21(9-13-25)14-17-32-18-15-24(16-19-32)30-28-31-26-4-2-3-5-27(26)33(28)20-22-6-10-23(29)11-7-22/h2-13,24H,14-20H2,1H3,(H,30,31)/i1D3
• Chave InChI: InChIKey=GXDALQBWZGODGZ-FIBGUPNXSA-N
• SMILES: [2H]C([2H])([2H])Oc1ccc(CCN2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)cc1