Azimilide Dihydrochloride

CAS: 149888-94-8

Ref. TR-A926950

Informação sobre produto

• Nome: Azimilide Dihydrochloride
• Sinónimos: 2,4-Imidazolidinedione, 1-[[[5-(4-chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-, hydrochloride (1:2), 2,4-Imidazolidinedione, 1-[[[5-(4-chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-, dihydrochloride (9CI), Azilimide dihydrochloride, NE 10064
• Marca: TRC
• Descrição: Applications Azimilide Dihydrochloride is an oral type III potassium channel blocker agent that blocks both the rapid activating component and the slow activating component of the delayed rectifier potassium current. Both preclinical and clinical studies have demonstrated the efficacy of azimilide and its safety in the treatment of supraventricular and ventricular tachyarrhythmia. Azimilide also is being studied in a worldwide multicenter trial for prevention of sudden cardiac death in patients after myocardial infarction. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Tran, H.T., et al.: Heart. Dis., 1, 114 (1999); Conway, E., et al.: Am. J. Cardiol., 102, 12 (2008); Carlson, M., et al.: Exp. Rev. Cardio. Therap., 3, 387 (2005); Dorian, P., et al.: J. Cardio. Pharm. Therap., 7, 211 (2002)

Propriedades químicas

• Peso molecular: 530.88
• Fórmula: C₂₃H₂₈ClN₅O₃·2ClH
• Cor/forma: Neat
• InChI: InChI=1S/C23H28ClN5O3.2ClH/c1-26-12-14-27(15-13-26)10-2-3-11-28-22(30)17-29(23(28)31)25-16-20-8-9-21(32-20)18-4-6-19(24)7-5-18;;/h4-9,16H,2-3,10-15,17H2,1H3;2*1H
• Chave InChI: InChIKey=HHPSICLSNHCSNZ-BYEGLACWSA-N
• SMILES: CN1CCN(CCCCN2C(=O)CN(N=Cc3ccc(-c4ccc(Cl)cc4)o3)C2=O)CC1.Cl.Cl