BDP 37

CAS: 191744-13-5

Ref. TR-B129500

Informação sobre produto

• Nome: BDP 37
• Sinónimos: 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one, CX 614, LiD 37, 11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one, 2,3,6a,7,8,9-hexahydro-, 2,3,6a,7,8,9-Hexahydro-11H-[1,4]dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-on, Bdp 37, Cx 614

Descrição

Applications BDP 37 is a AMPA modulator that may exhibit therapeutic properties for treating Alzheimer's disease, schizophrenia, and mild cognitive impairment (MCI) (1,2,3,4). It is also an ampakine drug that facilitates activation of glutamatergic AMPA receptors.
References (1) Arai, A., et al.: J. Pharmacol. Exp. Ther., 278, 627 (1996)(2) Marini, A., et al.: J. Biol. Chem., 273, 29394 (1998)(3) Balkowiec, A., et al.: J. Neurosci., 22, 10399 (2002) (4) Dicou, E., et al.: Brain Res., 970, 221 (2003)

• Marca: TRC

Propriedades químicas

• Peso molecular: 247.25
• Fórmula: C₁₃H₁₃NO₄
• Cor/forma: Neat
• InChI: InChI=1S/C13H13NO4/c15-13-8-6-10-11(17-5-4-16-10)7-9(8)18-12-2-1-3-14(12)13/h6-7,12H,1-5H2
• Chave InChI: InChIKey=RQEPVMAYUINZRE-UHFFFAOYSA-N
• SMILES: O=C1c2cc3c(cc2OC2CCCN12)OCCO3