(5,5’-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6’-dichloro-3-hydroxy-3,3’-biindoline-2,2’-dione)-d8

CAS: 1303996-68-0

Ref. TR-B203572

Informação sobre produto

• Nome: (5,5’-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6’-dichloro-3-hydroxy-3,3’-biindoline-2,2’-dione)-d8
• Sinónimos: 3-[5-[2-[4-(1,2-benzothiazol-3-yl)-2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl]ethyl]-6-chloro-2-oxo-1,3-dihydroindol-3-yl]-5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-3-hydroxy-1H-indol-2-one

Descrição

Applications (5,5’-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6’-dichloro-3-hydroxy-3,3’-biindoline-2,2’-dione)-d8 is the labaeled analogue of (5,5’-Bis(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6,6’-dichloro-3-hydroxy-3,3’-biindoline-2,2’-dione) (B203570), a compound related to Ziprasidone (Z485000), which is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist. Used as an antipsychotic.
References Bench, C.J., et al.: Psychopharmacology, 112, 308 (1993), Goldstein, J.M.: Exp. Opin. Invest. Drugs, 4, 291 (1995)

• Marca: TRC

Propriedades químicas

• Peso molecular: 847.904
• Fórmula: C₄₂D₈H₃₂Cl₂N₈O₃S₂
• Cor/forma: Neat
• InChI: InChI=1S/C42H40Cl2N8O3S2/c43-31-23-33-29(21-25(31)9-11-49-13-17-51(18-14-49)38-27-5-1-3-7-35(27)56-47-38)37(40(53)45-33)42(55)30-22-26(32(44)24-34(30)46-41(42)54)10-12-50-15-19-52(20-16-50)39-28-6-2-4-8-36(28)57-48-39/h1-8,21-24,37,55H,9-20H2,(H,45,53)(H,46,54)/i13D2,14D2,17D2,18D2
• SMILES: [2H]C1([2H])N(CCc2cc3c(cc2Cl)NC(=O)C3C2(O)C(=O)Nc3cc(Cl)c(CCN4CCN(c5nsc6ccccc56)CC4)cc32)C([2H])([2H])C([2H])([2H])N(c2nsc3ccccc23)C1([2H])[2H]