1-Benzyl 2-Methyl (2R)-5-Oxopyrrolidine-1,2-dicarboxylate

CAS: 690211-34-8

Ref. TR-B275445

Informação sobre produto

• Nome: 1-Benzyl 2-Methyl (2R)-5-Oxopyrrolidine-1,2-dicarboxylate
• Sinónimos: 1-Benzyl 2-Methyl (R)-5-Oxopyrrolidine-1,2-dicarboxylate

Descrição

Applications 1-Benzyl 2-Methyl (2R)-5-Oxopyrrolidine-1,2-dicarboxylate is an intermediate in the synthesis of (+)-Anatoxin A Hydrochloride (A653360), a secondary, bicyclic amine alkaloid and cyanotoxin with acute neurotoxicity. The toxin is produced by at least four different genera of cyanobacteria and has been reported in North America, Europe, Africa, Asia, and New Zealand. Symptoms of anatoxin exposure are loss of coordination, muscular fasciculations, convulsions and death by respiratory paralysis.
References Ueno, Y., et al.: Carcinogenesis, 17, 1317 (1996); Yu, F., et al.: J. Agric Food Chem., 50, 4176 (2002); Welker, M., et al.: Environ. Toxicol., 17, 367 (2002); Furey, A., et al.: Toxicon, 41, 297 (2003);

• Marca: TRC

Propriedades químicas

• Peso molecular: 277.27
• Fórmula: C₁₄H₁₅NO₅
• Cor/forma: Neat
• InChI: InChI=1S/C14H15NO5/c1-19-13(17)11-7-8-12(16)15(11)14(18)20-9-10-5-3-2-4-6-10/h2-6,11H,7-9H2,1H3/t11-/m1/s1
• Chave InChI: InChIKey=MBOBZGBHABMDMC-LLVKDONJSA-N
• SMILES: COC(=O)[C@H]1CCC(=O)N1C(=O)OCc1ccccc1