Biphenylindanone A

CAS: 866823-73-6

Ref. TR-B397910

Informação sobre produto

• Nome: Biphenylindanone A
• Sinónimos: 3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylic Acid, Biphenyl indanone A, MRLSD 230, 3'-((2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yloxy)methyl)biphenyl-4-carboxylic acid, 3′-(((2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy)methyl)-[1,1′-biphenyl]-4-carboxylic acid, 3′-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl][1,1′-biphenyl]-4-carboxylic acid, Bina, Biphenyl-indanone a, Mrlsd 230, [1,1'-Biphenyl]-4-carboxylic acid, 3'-[[(2-cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-, 3'-[[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl]biphenyl-4-carboxylic acid, 3′-[[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl]biphenyl-4-carboxylic acid

Descrição

Applications Biphenylindanone A is an orally active metabotropic glutamate subtype 2 receptor positive allosteric modulator.
References Dhanya, R.P., et al.: J. Med. Chem., 54, 342 (2011); Sidique, S., et al.: J. Med. CHem., 55, 9434 (2012); Delille, H.K., et al.: Neuropharmacol., 62, 2184 (2012);

• Marca: TRC

Propriedades químicas

• Peso molecular: 454.56
• Fórmula: C₃₀H₃₀O₄
• Cor/forma: Neat
• InChI: InChI=1S/C30H30O4/c1-18-19(2)28-25(15-26(29(28)31)22-7-3-4-8-22)16-27(18)34-17-20-6-5-9-24(14-20)21-10-12-23(13-11-21)30(32)33/h5-6,9-14,16,22,26H,3-4,7-8,15,17H2,1-2H3,(H,32,33)
• Chave InChI: InChIKey=KMKBEESNZAPKMP-UHFFFAOYSA-N
• SMILES: Cc1c(OCc2cccc(-c3ccc(C(=O)O)cc3)c2)cc2c(c1C)C(=O)C(C1CCCC1)C2