BGP 15

CAS: 66611-37-8

Ref. TR-B411990

Informação sobre produto

• Nome: BGP 15
• Sinónimos: N-[2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide Dihydrochloride

Descrição

Applications BGP 15 is a calcipotriene-based vitamin D3 analog that inhibits poly(ADP-ribose) polymerasesis (PARP), a class of enzymes that regulate DNA repair and apoptosis (1). BGP 15 is also a cardioprotective agent (2). Also, BPG 15 improves mitochondrial function, protects neurons from dying in vitro and in vivo, and promotes cardiac innervation in vivo.
References (1) Berkovich, L., et al.: Anticancer Drugs. 21, 609 (2010) (2) Szabados, E., et al. Biochem Pharmacol. 59, 937 (2000)

• Marca: TRC

Propriedades químicas

• Peso molecular: 351.27
• Fórmula: C₁₄H₂₂N₄O₂HCl
• Cor/forma: Neat
• InChI: InChI=1S/C14H22N4O2.2ClH/c15-14(12-5-4-6-16-9-12)17-20-11-13(19)10-18-7-2-1-3-8-18;;/h4-6,9,13,19H,1-3,7-8,10-11H2,(H2,15,17);2*1H
• Chave InChI: InChIKey=ISGGVCWFTPTHIX-UHFFFAOYSA-N
• SMILES: Cl.Cl.N=C(NOCC(O)CN1CCCCC1)c1cccnc1