1,4-Bis([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole

Ref. TR-B412960

Informação sobre produto

• Nome: 1,4-Bis([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole

Descrição

Applications 1,4-Bis([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole is derived from 5-([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazole (B397925), which is a structural isomer of Bifonazole (B383400) that is an anti-fungal agent used in the treatment of skin diseases. Bifonazole causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.
References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);

• Marca: TRC

Propriedades químicas

• Peso molecular: 552.71
• Fórmula: C₄₁H₃₂N₂
• Cor/forma: Neat
• InChI: InChI=1S/C41H32N2/c1-5-13-31(14-6-1)33-21-25-36(26-22-33)40(35-17-9-3-10-18-35)39-29-43(30-42-39)41(37-19-11-4-12-20-37)38-27-23-34(24-28-38)32-15-7-2-8-16-32/h1-30,40-41H
• Chave InChI: InChIKey=GNKMHHWRXCPMFS-UHFFFAOYSA-N
• SMILES: c1ccc(-c2ccc(C(c3ccccc3)c3cn(C(c4ccccc4)c4ccc(-c5ccccc5)cc4)cn3)cc2)cc1