1,6:3,4-Bis-[O-(2,3-dimethoxybutane-2,3-diyl)]-2-O-trifluoromethanesulphonyl-5-O-benzolyl-myo-inositol

CAS: 1068089-34-8

Ref. TR-B427000

Informação sobre produto

• Nome: 1,6:3,4-Bis-[O-(2,3-dimethoxybutane-2,3-diyl)]-2-O-trifluoromethanesulphonyl-5-O-benzolyl-myo-inositol
• Sinónimos: 1,6-O-[(1R,2R)-1,2-Dimethoxy-1,2-dimethyl-1,2-ethanediyl]-3,4-O-[(1S,2S)-1,2-dimethoxy-1,2-dimethyl-1,2-ethanediyl]-myo-inositol 5-Benzoate 2-(1,1,1-Trifluoro-methanesulfonate)

Descrição

Applications One of the scyllo-Inositol derivatives having effects on amyloid β peptide aggregation. Scyllo-Inositol has shown promise as a potential therapeutic for Alzheimer's disease, by directly interacting with the amyloid β (Aβ) peptide to inhibit Aβ42 fiber formation.
References McLaurin, J., et al.: J. Biol. Chem., 275, 18495 (2000), Hardy, J., et al.: Science, 297, 353 (2002), Cohen, T., et al.: Biochemistry, 45, 4727 (2006),

• Marca: TRC

Propriedades químicas

• Peso molecular: 644.61
• Fórmula: C₂₆H₃₅F₃O₁₃S
• Cor/forma: Neat
• InChI: InChI=1S/C26H35F3O13S/c1-22(33-5)24(3,35-7)40-18-16(38-22)15(37-21(30)14-12-10-9-11-13-14)17-19(20(18)42-43(31,32)26(27,28)29)41-25(4,36-8)23(2,34-6)39-17/h9-13,15-20H,1-8H3/t15-,16-,17?,18+,19-,20?,22+,23-,24+,25-/m1/s1
• Chave InChI: InChIKey=JKOKAMIFWNDNGM-UMTNBQNXSA-N
• SMILES: CO[C@@]1(C)O[C@@H]2C(OS(=O)(=O)C(F)(F)F)[C@@H]3O[C@@](C)(OC)[C@](C)(OC)OC3[C@H](OC(=O)c3ccccc3)[C@H]2O[C@]1(C)OC