4',5'-Bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic Acid

CAS: 1042084-20-7

Ref. TR-B431950

Informação sobre produto

• Nome: 4',5'-Bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic Acid
• Sinónimos: 4',5'-di-1,3,2-Dithiarsolan-2-yl-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic Acid, 6-CrAsH-EDT2
• CAS: 1042084-20-7

Descrição

Applications 4',5'-Bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic Acid, is used as a probe able to bind efficiently and selectively to Cys-tagged proteins. The interaction with the protein is detected by an increase of the fluorescence emission of CrAsH.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Genin, E., et al.: J. Amer. Chem. Soc., 130, 8596 (2008); Gaspersic, J., et al: FEBS Journal, 2038 (2010);

• Marca: TRC

Propriedades químicas

• Peso molecular: 708.5094
• Fórmula: C₂₅H₁₈As₂O₇S₄
• Cor/forma: Light Orange to Orange Solid
• InChI: InChI=1S/C25H18As2O7S4/c28-17-5-3-14-21(19(17)26-35-7-8-36-26)33-22-15(4-6-18(29)20(22)27-37-9-10-38-27)25(14)16-11-12(23(30)31)1-2-13(16)24(32)34-25/h1-6,11,28-29H,7-10H2,(H,30,31)
• Chave InChI: InChIKey=ONYYUXVYZJHFJD-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)c([As]3SCCS3)c2Oc2c1ccc(O)c2[As]1SCCS1