Bleomycin Sulfate (A mixture of bleomycin sulfate salts) (>90%)

CAS: 9041-93-4

Ref. TR-B595800

Informação sobre produto

• Nome: Bleomycin Sulfate (A mixture of bleomycin sulfate salts) (>90%)
• Sinónimos: Bleomycin, sulfate (salt), Blenoxane, Bleomycin sulfate, Blexane, 3-[[2-[2-[2-[[2-[[(2S,3S,4R)-4-[[(2R,3S)-3-[(2S,3S,4R,5S,6R)-3-[(2S,3S,4R,5S,6R)-4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(1H-imidazol-4-yl)-2-[[2-(propylaminomethyl)pyrimidine-4-carbonyl]amino]propanoyl]amino]-3-hydroxy-2-methyl-pentanoyl]amino]-3-hydroxy-butanoyl]amino]ethyl]thiazol-4-yl]thiazole-5-carbonyl]amino]propyl-dimethyl-sulfonium, Bleomycin Sulfate From Streptomyces Verticillus, Bleomycin, sulfate (salt), Bleomycine Sulfate

Descrição

Stability Hygroscopic
Applications Bleomycin Sulfate is part of a group of related glycopeptide antibiotics. Bleomycin A2 is the main component of the bleomycin employed clinically.Antineoplastic.
References Umezawa, et al.: J. Antibiot., 19, 200 (1966), Burger, R.M., et al.: Life Sci., 28, 715 (1981), Marugesan, N., et al.: J. Biol. Chem., 257, 8600 (1982), Saito, S., et al.: J. Antibiot., 36, 92 (1983),

• Marca: TRC

Propriedades químicas

• Peso molecular: 3036.21
• Fórmula: C₅₀H₇₂N₁₇O₂₁S₂•R•xHSO₄
• Pureza: >90%
• Cor/forma: White to Yellow Solid
• InChI: 2*(H2,1,2,3,4)/t20-,21+,22+,23-,24-,28-,29+,33-,34-,35-,36+,37+,38-,39-,40-,41-,42-,52+,53-, 1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6, InChI=1S/C55H84N20O21S2.C55H83N17O21S3.2H2O4S/c1-19-32(72-45(75-43(19)58)24(11-30(57)79)67-12-23(56)44(59)85)49(89)74-34(40(25-13-63-18-68-25)94-53-42(38(83)36(81)28(14-76)93-53)95-52-39(84)41(96-55(62)91)37(82)29(15-77)92-52)50(90)69-21(3)35(80)20(2)46(86)73-33(22(4)78)48(88)65-10-7-31-70-27(17-97-31)51-71-26(16-98-51)47(87)64-8-5-6-9-66-54(60)61, 14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88), 21-,22+,23+,24-,25-,29-,30+,34-,35-,36-,37+,38+,39-,40-,41-,42-,43-,53+,54-, , /m00../s1, 2*1-5(2,3)4/h13,16-18,20-24,28-29,33-42,52-53,67,76-78,80-84H,5-12,14-15,56H2,1-4H3,(H2,57,79)(H2,59,85)(H2,62,91)(H,63,68)(H,64,87)(H,65,88)(H,69,90)(H,73,86)(H,74,89)(H2,58,72,75)(H4,60,61,66)
• SMILES: Cc1c(C(=O)NC(C(=O)NC(C)C(O)C(C)C(=O)NC(C(=O)NCCc2nc(-c3nc(C(=O)NCCC[S+](C)C)cs3)cs2)C(C)O)C(OC2OC(CO)C(O)C(O)C2OC2OC(CO)C(O)C(OC(=N)[O-])C2O)c2cnc[nH]2)nc(C(CC(N)=O)NCC(N)C(N)=O)[nH]c1=N.O=S(=O)(O)O