2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine

CAS: 170729-79-0

Ref. TR-B657155

Informação sobre produto

• Nome: 2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine
• Sinónimos: (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)-morpholine, [2R-[2α(S*),3α]]-2-[1-[3,5-bis(trifluoromethyl)phenyl], Morpholine,2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-[2R-[2a(S*),3a]], (2R,3S)-2-{(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholine
• CAS: 170729-79-0

Descrição

Applications A metabolite of Aprepitant.
References Ballard, T., et al.: Eur. J. Pharmacol., 412, 255 (2001), Campos, D., et al.: J. Clin. Oncol., 19, 1759 (2001), Severini, C., et al.: Pharmacol. Rev., 54, 285 (2002)

• Marca: TRC

Propriedades químicas

• Peso molecular: 437.35
• Fórmula: C₂₀H₁₈F₇NO₂
• Cor/forma: Neat
• InChI: InChI=1S/C20H18F7NO2/c1-11(13-8-14(19(22,23)24)10-15(9-13)20(25,26)27)30-18-17(28-6-7-29-18)12-2-4-16(21)5-3-12/h2-5,8-11,17-18,28H,6-7H2,1H3/t11-,17-,18+/m0/s1
• Chave InChI: InChIKey=AFBDSAJOMZYQAI-FJNPEDAXSA-N
• SMILES: C[C@H](O[C@H]1OCCN[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1