3-Benzyl-6-bromo-2-chloroquinoline
CAS: 654655-68-2
Ref. TR-B674545
1g | Descontinuado | ||
250mg | Descontinuado | ||
500mg | Descontinuado |
Informação sobre produto
- 6-Bromo-2-chloro-3-(phenylmethyl)quinoline
- 3-Benzyl-6-Bromo-2-Chloroquinoline
Applications 3-Benzyl-6-bromo-2-chloroquinoline is an intermediate in the synthesis of (αS,βR)-Bedaquiline (B119540), which is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References Cheepsattayakorn, A., et al.: Anti-Infect. Drug. Discover.,7, 141 (2012); de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);