5-(2-Bromoethyl)benzofuran

CAS: 133034-06-7

Ref. TR-B680450

Informação sobre produto

• Nome: 5-(2-Bromoethyl)benzofuran
• Sinónimos: 5-(2-bromoethyl)-1-benzofuran, Benzofuran, 5-(2-bromoethyl)-, 5-(2-Bromoethyl)benzo[2,3-b]furan

Descrição

Applications 5-(2-Bromoethyl)benzofuran is an impurity of Darifenacin (D193400), a drug that blocks the M3 muscarinic acetylcholine receptor and used to treat urinary incontinence. 5-(2-Bromoethyl)benzofuran can also be used to prepare 3,6-disubstituted azabicyclo[3.1.0]hexane derivatives as muscarinic receptor antagonists.
References Mehta, A., et al.: PCT Int. Appl. WO 2004052857 A1 20040624 (2004); Beaumont, K.C., et al.: Xenobiotica, 28, 63 (1998); Chapple, C.R., et al.: Expert Opin. Invest. Drugs, 13, 1493 (2004); Haab, F., et al.: Eur. Urol., 45, 420 (2004)

• Marca: TRC

Propriedades químicas

• Peso molecular: 225.082
• Fórmula: C₁₀H₉BrO
• Cor/forma: Neat
• InChI: InChI=1S/C10H9BrO/c11-5-3-8-1-2-10-9(7-8)4-6-12-10/h1-2,4,6-7H,3,5H2
• Chave InChI: InChIKey=IYTHLIKUXKPFMY-UHFFFAOYSA-N
• SMILES: BrCCc1ccc2occc2c1