Informação sobre produto
- 1,1-Dimethylethylsulfinamide
- 2-Methyl-2-propanesulfinamide
- 2-Methylpropan-2-sulfinamide
- 2-Methyl-2-propanesulfinamide
- 2-Methyl-2-Propanesulfinamide
- 2-Methyl-2-Propanesulfinamide, Racemic
- 2-Methyl-Propane-2-Sulfinic Acid Amide
- 2-Methylpropane-1-Sulfinamide
- 2-Propanesulfinamide, 2-methyl-
- Racemic Tert Butylsulfinamide
- Ver mais sinónimos
- T-Butylsulfinamide
- Tert-Butylsulfinamide
- Tert-Butylsulphinamide
- tert-Butanesulfinamide
Applications tert-Butylsulfinamide can be readily transformed into P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins. tert-Butylsulfinamide is also used as a reagent in the synthetic preparation of amide series as BACE1 inhibitor and potential anti-Alzheimer’s drug.
References Szallasi, A., et al.: Pharmacol. Rev., 51, 159 (1999), Montell, C., et al.: Mol. Cell., 9, 229 (2002), Ryu, C., et al.: Bioorg. Med. Chem. Lett., 14, 1751 (2004), Suh, Y., et al.: J. Med. Chem., 48, 5823 (2005); Woltering, T. J., et al.: Bioorg. Med. Chem. Lett., 23, 4239 (2013)
Propriedades químicas
Consulta técnica sobre: TR-B693900 tert-Butylsulfinamide
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