(4R)-tert-Butyldimethylsilyl 4-((3S,9R,10S,13R,14R,17R)-10,13-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

Ref. TR-B723440

Informação sobre produto

• Nome: (4R)-tert-Butyldimethylsilyl 4-((3S,9R,10S,13R,14R,17R)-10,13-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

Descrição

Applications (4R)-tert-Butyldimethylsilyl 4-((3S,9R,10S,13R,14R,17R)-10,13-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate is an intermediate in the synthesis of 5α-Cholesta-7,24-diene-3β-ol (C431505), which is the derivative of Zymosterol (Z701520). It can also be used for identification of a new plasma biomarker of Alzheimer's disease using metabolomics technology.
References Sato, Y., et al.: J. Lipid Res., 53, 567 (2012); Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934);

• Marca: TRC

Propriedades químicas

• Peso molecular: 572.95
• Fórmula: C₃₅H₆₀O₄Si
• Cor/forma: White Solid
• InChI: InChI=1S/C35H60O4Si/c1-24(12-17-31(36)39-40(7,8)33(2,3)4)28-15-16-29-27-14-13-25-23-26(38-32-11-9-10-22-37-32)18-20-34(25,5)30(27)19-21-35(28,29)6/h14,24-26,28-30,32H,9-13,15-23H2,1-8H3/t24-,25?,26+,28-,29+,30+,32?,34+,35-/m1/s1
• Chave InChI: InChIKey=XBIQPYOHWXHGHW-LBWICSHXSA-N
• SMILES: C[C@H](CCC(=O)O[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2C3=CCC4C[C@@H](OC5CCCCO5)CC[C@]4(C)[C@H]3CC[C@@]21C