N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine

CAS: 231278-20-9

Ref. TR-B807825

Informação sobre produto

• Nome: N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine
• Sinónimos: N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodoquinazolin-4-amine, 4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-, 4-[[3-Chloro-4-(3-fluorobenzyloxy)phenyl]amino]-6-iodoquinazoline, 6-Iodo-(4-(3-Fluorobenzyloxy)-3-Chlorophenyl)-Quinazolin-4Yl)Amine, 6-Iodo-4-[3-chloro-4-(3-fluorobenzyloxy)anilino]quinazoline, Lapatinib's intermediate, N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazoline-4-amine, N-{3-Chloro-4-[(3-fluorophenyl)-methoxy]-phenyl}-6-iodo-4-quinazolinamine, N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine, N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodoquinazolin-4-amine, [3-Chloro-4-(3-fluoro-benzyloxy)-phenyl]-(6-iodo-quinazolin-4-yl)-amine, [3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl](6-iodoquinazolin-4-yl)amine

Descrição

Applications 3-[(4-Bromophenyl)(methyl)amino]propanoic acid (cas# 231278-20-9) is a quinazoline derivative and an aryl iodide. 3-[(4-Bromophenyl)(methyl)amino]propanoic acid has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.
References Zhang, Y.; et al.: Bioorg. Med. Chem. Lett., 27, 1584 (2017); Lin, S.; Eur. J. Med. Chem., 127, 442 (2017).

• Marca: TRC

Propriedades químicas

• Peso molecular: 505.71
• Fórmula: C₂₁H₁₄ClFIN₃O
• Cor/forma: Neat
• InChI: InChI=1S/C21H14ClFIN3O/c22-18-10-16(5-7-20(18)28-11-13-2-1-3-14(23)8-13)27-21-17-9-15(24)4-6-19(17)25-12-26-21/h1-10,12H,11H2,(H,25,26,27)
• Chave InChI: InChIKey=UHFPFDMMKYQMLC-UHFFFAOYSA-N
• SMILES: Fc1cccc(COc2ccc(Nc3ncnc4ccc(I)cc34)cc2Cl)c1