2-Chlorophenol - 13C6

CAS: 1975217-09-4

Ref. TR-C360552

Informação sobre produto

• Nome: 2-Chlorophenol - 13C6
• Sinónimos: 2-Chlorophenol (ring-13C6), 2-Chlorophenol-1,2,3,4,5,6-13C6

Descrição

Applications 2-Chlorophenol is an intermediate used in the synthesis of Diclofenamide-13C6 (D436532), which is a labeled Diclofenamide, a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP).
References Brzozowski, Z. et al.: Eur. J. Med. Chem., 46, 3656 (2010); Tawil, R. et al.: Ann. Neurol., 47, 46 (2000); Casey, J. et al.: J. Med. Chem., 47, 2337 (2004);

• Marca: TRC

Propriedades químicas

• Peso molecular: 134.512
• Fórmula: C₆H₅ClO
• Cor/forma: Neat
• InChI: InChI=1S/C6H5ClO/c7-5-3-1-2-4-6(5)8/h1-4,8H/i1+1,2+1,3+1,4+1,5+1,6+1
• Chave InChI: InChIKey=ISPYQTSUDJAMAB-IDEBNGHGSA-N
• SMILES: O[13c]1[13cH][13cH][13cH][13cH][13c]1Cl