2-Chloro-5-(chloromethyl)thiazole

CAS: 105827-91-6

Ref. TR-C367145

Informação sobre produto

• Nome: 2-Chloro-5-(chloromethyl)thiazole
• Sinónimos: 2-chloro-5-(chloromethyl)-1,3-thiazole, 2-Chloro-5-(Chloromethyl)-1,3-Thiazole, 2-Chloro-5-Chloromethyl-Thiazole, 2-Chloro-5-chloro methylthiazole, 2-Chloro-5-thiazolylmethyl chloride, 5-Chloromethyl-2-chloro-1,3-thiazole, CCT, Thiazole, 2-chloro-5-(chloromethyl)-
• CAS: 105827-91-6

Descrição

Applications 2-Chloro-5-(chloromethyl)thiazole is a useful synthetic intermediate used in the synthesis of Ritonavir (R535000); a second generation anti-AIDS drug and a selective HIV protease inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Meng, F., et al.: Guangzhou Huagong, 40, 66 (2012); Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994); Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003); Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005); Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006)

• Marca: TRC

Propriedades químicas

• Peso molecular: 168.04
• Fórmula: C₄H₃Cl₂NS
• Cor/forma: Neat
• InChI: InChI=1S/C4H3Cl2NS/c5-1-3-2-7-4(6)8-3/h2H,1H2
• Chave InChI: InChIKey=VRMUIVKEHJSADG-UHFFFAOYSA-N
• SMILES: ClCc1cnc(Cl)s1