(2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne

CAS: 635708-74-6

Ref. TR-C367610

Informação sobre produto

• Nome: (2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne

Descrição

Applications (2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne is a byproduct in the synthesis of Terbinafine Hydrochloride (T107500); an orally active, antimycotic allylamine related to Naftifine. It is a specific inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Also antifungal.
References Kazakov, P.V., et al.: Pharm. Chem. J., 40, 452 (2006); Petranyi, G., et al.: Science, 224, 1239 (1984); Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985); Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999)

• Marca: TRC

Propriedades químicas

• Peso molecular: 156.65
• Fórmula: C₉H₁₃Cl
• Cor/forma: Neat
• InChI: InChI=1S/C4H7Cl/c1-2-3-4-5/h2-3H,4H2,1H3/b3-2-
• Chave InChI: InChIKey=YTKRILODNOEEPX-IHWYPQMZSA-N
• SMILES: CC(C)(C)C#C/C=C\CCl