(11b,16a)-9-Chloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-21-[(methylsulfonyl)oxy]-pregna-1,4-diene-3,20-dione (Mometasone Impurity R)

CAS: 1370190-08-1

Ref. TR-C374115

Informação sobre produto

• Nome: (11b,16a)-9-Chloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-21-[(methylsulfonyl)oxy]-pregna-1,4-diene-3,20-dione (Mometasone Impurity R)
• Sinónimos: 9-Chloro-11beta-hydroxy-16alpha-methyl-21-[(methylsulfonyl)oxy]-3,20-dioxopregna-1,4-dien-17-yl Furan-2-carboxylate, Pregna-1,4-diene-3,20-dione, 9-chloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-21-[(methylsulfonyl)oxy]-, (11ß,16a)-, 9-Chloro-11ß-hydroxy-16a-methyl-21-[(methylsulfonyl)oxy]-3,20-dioxopregna-1,4-dien-17-yl Furan-2-carboxylate, Mometasone Furoate Imp. R (EP)

Descrição

Applications (11β,16α)-9-Chloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-21-[(methylsulfonyl)oxy]-pregna-1,4-diene-3,20-dione is derived from Icomethasone 21-Mesylate (I164110), which is a derivative of Icomethasone (I164100), used in the preparation of Mometasone (M489995).

• Marca: TRC

Propriedades químicas

• Peso molecular: 581.07
• Fórmula: C₂₈H₃₃ClO₉S
• Cor/forma: Neat
• InChI: InChI=1S/C28H33ClO9S/c1-16-12-20-19-8-7-17-13-18(30)9-10-25(17,2)27(19,29)22(31)14-26(20,3)28(16,23(32)15-37-39(4,34)35)38-24(33)21-6-5-11-36-21/h5-6,9-11,13,16,19-20,22,31H,7-8,12,14-15H2,1-4H3/t16-,19+,20+,22+,25+,26+,27+,28+/m1/s1
• Chave InChI: InChIKey=AVTGVLGPYCPSRO-OKCRLJKSSA-N
• SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c1ccco1)C(=O)COS(C)(=O)=O