1-(3-Chlorophenyl)piperazine

CAS: 6640-24-0

Ref. TR-C379590

Informação sobre produto

• Nome: 1-(3-Chlorophenyl)piperazine
• Sinónimos: Piperazine, 1-(3-chlorophenyl)-, Piperazine, 1-(m-chlorophenyl)- (8CI), 1-(m-Chlorophenyl)piperazine, 4-(3-Chlorophenyl)piperazine, N-(3-Chlorophenyl)piperazine, N-(m-Chlorophenyl)piperazine, NSC 49307, m-CPP, mCPP, mCPP (pharmaceutical), meta-Chlorophenylpiperazine, 1-(3-Chlorphenyl)-piperazine, 1-(M-Chlorophenyl)Piperazine, 1-(M-Clorofenil)Piperazina, 1-(m-Chlorphenyl)piperazin, 3-Chlorophenyl piperazine, 3-Chlorphenylpiperazine, Nsc 49307, Piperazine, 1-(3-chlorophenyl)-, Piperazine, 1-(m-chlorophenyl)-, 1-(3-Chlorophenyl)-piperazine

Descrição

Applications It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone (1,2,3). The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.
References (1) Bo Wen, et al.: Drug Metab. Dispos., 36, 841 (2008) (2) Maes, M., et al.: J. Clin. Psychopharmacol., 17, 358 (1997) (3) Fiorella, D., et al.: Psychopharmacology, 119, 220 (1995)

• Marca: TRC

Propriedades químicas

• Peso molecular: 196.68
• Fórmula: C₁₀H₁₃ClN₂
• Cor/forma: Neat
• InChI: InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2
• Chave InChI: InChIKey=VHFVKMTVMIZMIK-UHFFFAOYSA-N
• SMILES: Clc1cccc(N2CCNCC2)c1