4-Chloro-2-methylbenzoic Acid

CAS: 7499-07-2

Ref. TR-C427685

Informação sobre produto

• Nome: 4-Chloro-2-methylbenzoic Acid
• Sinónimos: 4-Chloro-o-toluic Acid, NSC 407521
• CAS: 7499-07-2

Descrição

Applications 4-Chloro-2-methylbenzoic Acid is used as a reagent in organic synthesis including that of diarylamides which have a pyrimidinyl pyridine scaffold which show promising anti-proliferative effects on melanoma cancer cell lines. It is also used in the preparation of analogs of lenalidomide and pomalidomide for use as anti inflammatory and antitumor agents.
References Abdelazem, A., et al.: Bioorg. Med. Chem. Lett., 26, 1301 (2016); Ruchelman, A., et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013);

• Marca: TRC

Propriedades químicas

• Peso molecular: 170.59
• Fórmula: C₈H₇ClO₂
• Cor/forma: Neat
• InChI: InChI=1S/C8H7ClO2/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4H,1H3,(H,10,11)
• Chave InChI: InChIKey=XXFKOBGFMUIWDH-UHFFFAOYSA-N
• SMILES: Cc1cc(Cl)ccc1C(=O)O