(2S,4R)-4-((3-Chloro-7-methoxyquinoxalin-2-yl)oxy)-2-(methoxycarbonyl)pyrrolidinium Methanesulfonate

CAS: 1425038-20-5

Ref. TR-C428933

Informação sobre produto

• Nome: (2S,4R)-4-((3-Chloro-7-methoxyquinoxalin-2-yl)oxy)-2-(methoxycarbonyl)pyrrolidinium Methanesulfonate
• Sinónimos: (4R)-4-[(3-Chloro-7-methoxy-2-quinoxalinyl)oxy]-L-proline Methyl Ester Methanesulfonate
• Marca: TRC
• Descrição: Applications (2S,4R)-4-((3-Chloro-7-methoxyquinoxalin-2-yl)oxy)-2-(methoxycarbonyl)pyrrolidinium Methanesulfonate is an antiviral agent and Grazoprevir (M424985) intermediate. Grazoprevir is a second-generation NS3/4A protease inhibitor. It is a COVID19-related research product.References Alric, L., et al.: Expert Opin. Pharmaco., 17, 735 (2016); Gentile, I., et al.: Expert Opin. Inv. Drug., 25, 557 (2016); Sulejmani, N., et al.: Expert Opin. Drug Met., 12, 353 (2016); Roensholt, F.F., et al.: Future Virol., 10, 691 (2015)

Propriedades químicas

• Peso molecular: 433.86
• Fórmula: C₁₅H₁₆ClN₃O₄·CH₄O₃S
• Cor/forma: Neat
• InChI: InChI=1S/C15H16ClN3O4.CH4O3S/c1-21-8-3-4-10-11(5-8)19-14(13(16)18-10)23-9-6-12(17-7-9)15(20)22-2;1-5(2,3)4/h3-5,9,12,17H,6-7H2,1-2H3;1H3,(H,2,3,4)/t9-,12+;/m1./s1
• Chave InChI: InChIKey=CCZFBHQUONFINY-KATIXKQHSA-N
• SMILES: COC(=O)[C@@H]1C[C@@H](Oc2nc3cc(OC)ccc3nc2Cl)CN1.CS(=O)(=O)O