Clocortolone Acetate

CAS: 4258-85-9

Ref. TR-C583820

Informação sobre produto

• Nome: Clocortolone Acetate
• Sinónimos: 9-Chloro-6a-fluoro-11ß,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-acetate, SH 818, 9-Chloro-6a-fluoro-11ß,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-Acetate, (6a,11ß,16a)-21-(Acetyloxy)-9-chloro-6-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, (6α,11β,16α)-21-(Acetyloxy)-9-chloro-6-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, 4258-85-9, 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate, Clocortolone acetate, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-chloro-6-fluoro-11-hydroxy-16-methyl-, (6α,11β,16α)-, Pregna-1,4-diene-3,20-dione, 9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methyl-, 21-acetate, Sh 818

Descrição

Applications Clocortolone Acetate is an intermediate in the synthesis of Clocortolone (C583800), an corticosteroid used in the treatment of skin inflammmation and other skin conditions arising for dermatoses.
References Rehm, K. et al.: Pharmaz. Zeit., 127, 888 (1982);

• Marca: TRC

Propriedades químicas

• Peso molecular: 452.94
• Fórmula: C₂₄H₃₀ClFO₅
• Cor/forma: Neat
• InChI: InChI=1S/C24H30ClFO5/c1-12-7-15-16-9-18(26)17-8-14(28)5-6-23(17,4)24(16,25)20(30)10-22(15,3)21(12)19(29)11-31-13(2)27/h5-6,8,12,15-16,18,20-21,30H,7,9-11H2,1-4H3/t12-,15+,16+,18+,20+,21-,22+,23+,24+/m1/s1
• Chave InChI: InChIKey=ARPLCFGLEYFDCN-CDACMRRYSA-N
• SMILES: CC(=O)OCC(=O)[C@H]1[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@@]21C