CX 546

CAS: 215923-54-9

Ref. TR-C858000

Informação sobre produto

• Nome: CX 546
• Sinónimos: 2,3-dihydro-1,4-benzodioxin-6-yl(piperidin-1-yl)methanone, (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone, 1-(1,4-Benzodioxan-6-ylcarbonyl)piperidine, 1-(2,3-Dihydro-1,4-benzodioxin-6-ylcarbonyl)piperidine, 1-(2,3-Dihydro-1,4-benzodioxine-6-carbonyl)piperidine, 2,3-Dihydro-1,4-Benzodioxin-6-Yl(Piperidin-1-Yl)Methanone, Bdp 17, Gr 87, Methanone, (2,3-dihydro-1,4-benzodioxin-6-yl)-1-piperidinyl-, Piperidine, 1-[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]-

Descrição

Applications It is one of a series of AMPA modulators for the potential treatment of Alzheimer's disease, schizophrenia, and mild cognitive impairment (MCI). An ampakine drug that facilitates activation of glutamatergic AMPA receptors.
References Partin, K., et al.: J. Neurosci.,16, 6634 (1996), Vanover, K., et al.: Eur. J. Pharmacol., 332, 115 (1997), Moser, P., et al.: Brain Res. Rev., 33, 275 (2000), Kinney, G., et al.: J. Pharmacol. Exp. Ther., 306, 116 (2003),

• Marca: TRC

Propriedades químicas

• Peso molecular: 247.29
• Fórmula: C₁₄H₁₇NO₃
• Cor/forma: Neat
• InChI: InChI=1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2
• Chave InChI: InChIKey=LJUNPHMOGNFFOS-UHFFFAOYSA-N
• SMILES: O=C(c1ccc2c(c1)OCCO2)N1CCCCC1