2-(2-Cyanophenyl)-1,3,2-dioxaborinane

CAS: 172732-52-4

Ref. TR-C987675

Informação sobre produto

• Nome: 2-(2-Cyanophenyl)-1,3,2-dioxaborinane
• Sinónimos: 2-(1,3,2-Dioxaborinan-2-yl)benzonitrile, 2-(1,3,2-Dioxaborinan-2-Yl)Benzonitrile, 2-(1,3,2-Dioxaborolan-2-Yl)Benzonitrile, 2-Cyanophenylboronic acid 1,3-propanediol ester
• CAS: 172732-52-4

Descrição

Stability Hygroscopic
Applications 2-(2-Cyanophenyl)-1,3,2-dioxaborinane is used in the synthesis of AMPA receptor antagonists in the treatment of neurological diseases causing dysfunction of glutamatergic neurotransmission. Also used in the small scale synthesis of Perampanel (P285520), an AMPA receptor antagonist.
References Hibi, S. et al.: J. Med. Chem., 55, 10584 (2012); McElhinny, C. et al.: Synthesis, 44, 57 (2012);

• Marca: TRC

Propriedades químicas

• Peso molecular: 187.0
• Fórmula: C₁₀H₁₀BNO₂
• Cor/forma: Neat
• InChI: InChI=1S/H3N/h1H3
• Chave InChI: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#Cc1ccccc1B1OCCCO1