N-Cyclopropylmethylnororipavine

CAS: 14728-69-9

Ref. TR-C988733

Informação sobre produto

• Nome: N-Cyclopropylmethylnororipavine
• Sinónimos: (5alpha)-17-(Cyclopropylmethyl)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxymorphinan-3-ol, 17-(Cyclopropylmethyl)-6,7,8,14-tetradehydro-4,5alpha-epoxy-6-methoxy-morphinan-3-ol
• CAS: 14728-69-9

Descrição

Applications N-Cyclopropylmethylnororipavine is an intermediate in synthesizing Oripavine (O675000), the major metabolite of Thebaine. Oripavine possesses an analgesic potency comparable to Morphine; it is not clinically useful due to severe toxicity and low therapeutic index. An opiate.
References Barber, R., et al.: J. Med. Chem., 18, 1074 (1975); Yamazoe, Y., et al.: J. Pharmacol., 31, 433 (1981)

• Marca: TRC

Propriedades químicas

• Peso molecular: 613.791
• Fórmula: C₂₁H₂₃NO₃
• Cor/forma: Neat
• InChI: InChI=1S/C33H52O10/c1-5-14-41-30(40)29-27(38)26(37)28(39)31(43-29)42-24(36)9-6-17(2)20-7-8-21-25-22(11-13-33(20,21)4)32(3)12-10-19(34)15-18(32)16-23(25)35/h5,17-23,25-29,31,34-35,37-39H,1,6-16H2,2-4H3/t17-,18+,19-,20-,21+,22+,23-,25+,26+,27+,28-,29+,31-,32+,33-/m1/s1/i10D2,15D2,19D
• Chave InChI: InChIKey=NMNJPAKLCVDDJX-CUDQUUBOSA-N
• SMILES: [2H]C1([2H])C[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@H]4[C@H](C)CCC(=O)O[C@@H]4O[C@H](C(=O)OCC=C)[C@@H](O)[C@H](O)[C@H]4O)[C@@H]3[C@H](O)C[C@@H]2C([2H])([2H])[C@]1([2H])O