Cyproterone

CAS: 2098-66-0

Ref. TR-C989090

Informação sobre produto

• Nome: Cyproterone
• Sinónimos: 3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1,2-dihydro-17-hydroxy-, (1beta,2beta)-, 3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1beta,2beta-dihydro-17-hydroxy- (8CI), Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-1alpha,2alpha-methylene- (7CI), (1beta,2beta)-6-Chloro-1,2-dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 1,2alpha-Methylene-6-chloro-6-17alpha-hydroxyprogesterone, 6-Chloro-1,2alpha-methylene-4,6-pregnadien-17alpha-ol-3,20-dione, 6-Chloro-17-hydroxy-1alpha,2alpha-methylenepregna-4,6-diene-3,20-dione, 6-Chloro-6-dehydro-17alpha-hydroxy-1,2alpha-methyleneprogesterone, SH 80881, SH 881, (1R,3aS,3bR,7aR,8aS,8bS,8cS,10aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1R,7aR,8aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1R,7aR,8bS,10aS)-1-acetyl-5-chloro-1-hydroxy-8b,10a-dimethyl-2,3,3a,3b,7a,8,8a,8b,8c,9,10,10a-dodecahydrocyclopenta[a]cyclopropa[g]phenanthren-7(1H)-one, (1β,2β)-6-Chloro-1,2-dihydro-17-hydroxy-3′H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 1,2α-Methylene-6-chloro-⁶-17α-hydroxyprogesterone, 3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 6-chloro-1-beta,2-beta-dihydro-17-hydroxy-, 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1,2-dihydro-17-hydroxy-, (1β,2β)-, 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1β,2β-dihydro-17-hydroxy-, 6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron, 6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteron [German], 6-Chloro-1,2α-methylene-4,6-pregnadien-17α-ol-3,20-dione, 6-Chloro-17-hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione, 6-Chloro-6-dehydro-17α-hydroxy-1,2α-methyleneprogesterone, Bay 94-8367, Bay94-8367, Ciproterona, Ciproterona [INN-Spanish], Ciproterone, Ciproterone [DCIT], Cyproteron, Cyproterone [INN:BAN], Cyproteronum, Cyproteronum [INN-Latin], Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-1α,2α-methylene-, Sh 80881, Sh 881, Unii-E61Q31Ek2F

Descrição

Impurity Cyproterone Acetate EP Impurity F
Applications Cyproterone (Cyproterone Acetate EP Impurity F) is an antiandrogen, suppresses Testosterone and its metabolites. Derivatives of Cyproterone are administered to patients suffering from hypersexuality and to help facilitate the sexual transformation of male-to-female transsexuals.
References Gracia, T., et al.: Toxicol. App. Pharmacol., 225, 142 (2007), Ahlin, G., et al.: J. Med. Chem., 51, 5932 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Bovee, T., et al.: J. Steroid Biochem. Mol. Biol., 118, 85 (2010),

• Marca: TRC

Propriedades químicas

• Peso molecular: 374.90
• Fórmula: C₂₂H₂₇ClO₃
• Cor/forma: Off White Solid
• InChI: InChI=1S/C22H27ClO3/c1-11(24)22(26)7-5-14-12-9-18(23)17-10-19(25)13-8-16(13)21(17,3)15(12)4-6-20(14,22)2/h9-10,12-16,26H,4-8H2,1-3H3/t12-,13+,14-,15-,16-,20-,21-,22-/m0/s1
• Chave InChI: InChIKey=DUSHUSLJJMDGTE-ZJPMUUANSA-N
• SMILES: CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@@]21C