(3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt

CAS: 1187966-91-1

Ref. TR-C989570

Informação sobre produto

• Nome: (3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt
• Sinónimos: (ßR,dS)-6-Cyclopropyl-10-fluoro-7,8-dihydro-ß,d-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid Sodium Salt
• CAS: 1187966-91-1

Descrição

Applications (3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt is an impurity of Pitavastatin (P531000), a competitive inhibitor of HMG-CoA reductase. Antilipemic.
References Aoki, T., et al.: Arzneim.-Forsch., 47, 904 (1997); Yamada, I., et al.: Xenobiotica, 33, 789 (2003); Park, S., et al.: Clin. Ther., 27, 1074 (2005)

• Marca: TRC

Propriedades químicas

• Peso molecular: 443.44
• Fórmula: C₂₅H₂₃FNNaO₄
• Cor/forma: Neat
• InChI: InChI=1S/C25H24FNO4.Na/c26-14-7-8-16-18(9-14)19(22(29)10-15(28)11-23(30)31)12-20-24(16)17-3-1-2-4-21(17)27-25(20)13-5-6-13;/h1-4,7-9,13,15,19,22,28-29H,5-6,10-12H2,(H,30,31);/q;+1/p-1/t15-,19?,22+;/m1./s1
• Chave InChI: InChIKey=LTQZCEXOGYHSRC-FNESQUEHSA-M
• SMILES: O=C(C[C@H](O)C[C@H](O)C1Cc2c(C3CC3)nc3ccccc3c2-c2ccc(F)cc21)O[Na]